Myocardial infarction and oral contraceptives.

During 1968-I972, 4 women of4I years or less were admitted with a myocardial infarction. Three ofthem had been taking oral contraceptives, all were moderate to heavy smokers, and the fathers of all of them had had a myocardial infarct after the age of 5o years. One had slight hypertension while using oral contraceptives and her serum cholesterol and lipids were increased. Details of all 3 cases are given and the current evidence of the relation between oral contraceptives and myocardial infarction reviewed.